潘玉峰 教授,博士生导师
电话:025-83790776
E-mail: pany@seu.edu.cn
Labweb: panylab.org
办公地点:南京市四牌楼2号,李文正北楼214室
个人简介:
2004年7月毕业于南开大学生物物理学专业获得学士学位,2009年7月毕业于中国科学院生物物理研究所神经生物学专业获得博士学位。自2009年9月起在美国著名的霍华德休斯医学研究所(Janelia Research Campus, Howard Hughes Medical Institute)做博士后工作。2014年受聘为东南大学生命科学研究院教授,2016年获得国家优秀青年基金以及江苏省杰出青年基金。现为生命科学与技术学院教授、博士生导师、副院长。
研究方向:动物行为的遗传与神经生物学机制
行为是如何产生的?先天获得的或是后天学习的?先天获得、后天学习的神经机制是什么?两性行为的天然差异是如何产生的?不同行为之间的转换与选择(比如睡眠、觅食、求偶)在分子和神经元水平的机制又是什么?本实验室以经典模式动物果蝇为模型,运用遗传学、光遗传学、行为学、分子生物学、电生理以及功能成像等技术手段研究动物行为的遗传与神经生物学机制。更多信息,请参见本实验室主页: panylab.org
近期代表性论文:
Han, C., Peng, Q., Sun, M., Jiang, X., Su, X., Chen, J., Ma, M., Zhu, H., Ji, X., Pan, Y. (2022) The doublesex gene regulates dimorphic sexual and aggressive behaviors in Drosophila. PNAS,119 (37) e2201513119. https://doi.org/10.1073/pnas.2201513119
Han, C., Peng, Q., Su, X., Xing, L., Ji, X., Pan, Y. (2022) A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms. Communications Biology, 5(1): p. 728. https://www.nature.com/articles/s42003-022-03664-7
Jiang, X. and Pan, Y. (2022) Neural Control of Action Selection Among Innate Behaviors. Neuroscience Bulletin, https://doi.org/10.1007/s12264-022-00886-x
Jia, Y., Jin, S., Hu, K., Geng, L., Han, C., Kang, R., Pang, Y., Ling, E., Tan, E., Pan, Y.* and Liu, W.* (2021) Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature Communications,12, 2698. (*Corresponding authors) https://doi.org/10.1038/s41467-021-23041-y
Chen, J., Jin, S., Chen, D., Cao, J., Ji, X., Peng, Q., Pan, Y. (2021) fruitless tunes functional flexibility of courtship circuitry during development.eLife, 10: e59224. https://elifesciences.org/articles/59224
Peng, Q, Chen, J, Pan, Y. (2021) From fruitless to sex: On the generation and diversification of an innate behavior. Genes, Brain and Behavior, e12772. doi:10.1111/gbb.12772. https://onlinelibrary.wiley.com/doi/full/10.1111/gbb.12772
Gao, C., Guo, C., Peng, Q., Cao, J., Shohat-Ophir, G., Liu, D., and Pan, Y. (2020) Sex and Death: Identification of Feedback Neuromodulation Balancing Reproduction and Survival. Neuroscience Bulletin,36, 1429–1440. https://doi.org/10.1007/s12264-020-00604-5
Wu, S., Guo, C., Zhao, H., Sun, M., Chen, J., Han, C., Peng, Q., Qiao, H., Peng, P., Liu, Y., Luo, S. D., and Pan, Y. (2019) Drosulfakinin signaling in fruitless circuitry antagonizes P1 neurons to regulate sexual arousal in Drosophila. Nature Communications,10, 4770. https://doi.org/10.1038/s41467-019-12758-6
Zhang, W., Guo, C., Chen, D., Peng, Q., and Pan, Y. (2018). Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons, Neuroscience Bulletin, 34, 1105–1110. https://doi.org/10.1007/s12264-018-0281-z
Chen, D., Sitaraman, D., Chen, N., Jin, X., Han, C., Chen, J., Sun, M., Baker, B.S., Nitabach, M.N., and Pan, Y. (2017). Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. Nature Communications, 8, 154. https://doi.org/10.1038/s41467-017-00087-5
Pan, Y.*, and Baker, B.S.* (2014). Genetic identification and separation of innate and experience-dependent courtship behaviors in Drosophila. Cell, 156, 236-248. (*Corresponding authors) https://doi.org/10.1016/j.cell.2013.11.041
Pan, Y., Meissner, G.W., and Baker, B.S. (2012). Joint control of Drosophila male courtship behavior by motion cues and activation of male-specific P1 neurons. PNAS, 109, 10065-10070. https://doi.org/10.1073/pnas.1207107109