芮梦龙 副研究员、硕士生导师
Emial: ruimenglong@seu.edu.cn
办公地址：东南大学江北校区汇川楼B202-2
个人简介：
2017年于东南大学获得博士学位，2018-2020于Temasek Life Sciences Laboratory从事博士后研究，2021年加入东南大学生命科学与技术学院。主持国家自然科学基金，江苏省自然科学基金，南京市留学人员科技创新项目择优资助，东南大学“至善青年学者”A项目。
研究方向：
1.神经重塑的微环境调控机制研究；
2.神经发育和动物行为的药理机制研究。
近期代表性论文：(# co-first author; * corresponding author)：
1. Menglong Rui*. Recent progress in dendritic pruning of Drosophila C4da sensory neurons. Open Biology. 2024 Jul;14(7):240059.
2. Wanting Wang, Menglong Rui*. Advances in understanding the roles of actin scaffolding and membrane trafficking in dendrite development. Journal of Genetics and Genomics. 2024 Jun 24: S1673-8527(24)00152-8.
3. Ziyang Gao, Erqian Huang, Wanting Wang, Lizhong Xu, Wanyue Xu, Ting Zheng, Menglong Rui*. Patronin regulates presynaptic microtubule organization and neuromuscular junction development in Drosophila.iScience. 2024 Jan 18;27(2):108944.
4. Menglong Rui*, Weiyu Kong, Wanting Wang, Ting Zheng, Su Wang*, Wei Xie. Droj2 Facilitates Somatosensory Neurite Sculpting via GTP-Binding Protein Arf102F in Drosophila. International Journal of Molecular Sciences. 2023 Aug 25;24(17):13213.
5. Wanyue Xu, Weiyu Kong, Ziyang Gao, Erqian Huang, Wei Xie, Su Wang*, Menglong Rui*. Establishment of a novel axon pruning model of Drosophila motor neuron. Biology Open. 2023 Jan 1;12(1): bio059535.
6. Menglong Rui#, Kay Siong Ng#, Quan Tang, Shufeng Bu, Fengwei Yu*. Protein phosphatase PP2A regulates microtubule orientation and dendrite pruning in Drosophila. EMBO Reports. 2020 Mar6;21 (5): e48843.
7. Menglong Rui#, Shufeng Bu#, Liang Yuh Chew#, Qiwei Wang, Fengwei Yu*. The membrane protein Raw regulates dendrite pruning via the secretory pathway. Development. 2020 Oct 9;147(19): dev191155.
8. Yan Wang#, Menglong Rui#, Quan Tang, Shufeng Bu, Fengwei Yu*. Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila. Elife. 2019 Mar 28;8: e39964.
9. Menglong Rui, Jinjun Qian, Lijuan Liu, Huihui Lv, Junhai Han, Zhengping Jia and Wei Xie*. The neuronal protein Neurexin directly interacts with the Scribble-Pix complex to stimulate F-actin assembly for synaptic vesicle clustering. Journal of Biological Chemistry. 2017 Sep 1;292(35): 14334-14348.
10. QuanTang, Menglong Rui, Shufeng Bu, Yan Wang, Liang Yuh Chew, and Fengwei Yu*. A microtubule polymerase is required for microtubule orientation and dendrite pruning in Drosophila. The EMBO Journal. 2020 May 18;39(10): e103549.
11. Huanhuan Zhang, Menglong Rui, Zhixin Ma, Sifan Gong, Shuliu Zhang, Qingxia Zhou, Congfeng Gan, Wenting Gong, Su Wang*. Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells. iScience. 2023 Nov 22;27(1):108545.
12. Xinwang Zhang, Menglong Rui, Guangmin Gan, Cong Huang, Jukang Yi, Huihui Lv, Wei Xie*. Neuroligin4 regulates synaptic growth via the bone morphogenetic protein (BMP) signaling pathway at the Drosophila neuromuscular junction. Journal of Biological Chemistry. 2017 Nov 3;292(44):17991-18005.
完整文章列表：https://orcid.org/0000-0002-1911-8397
