Fulong Wang
PhD, Associate Professor, PhD Supervisor
E-mail: fulongwang@seu.edu.cn
Mailing Address: Huichuan Building Room B305
2 Dongda Road, Pukou District, Nanjing, Jiangsu.
Biography
Dr. Wang is an associate professor of School of Life Science and Technology at Southeast University since Oct 2023. He received his undergraduate, Ms.C, Ph.D. and postdoctoral education/training in Nanjing, Shanghai, Vancouver, and Texas/New Mexico.
Research interest
Lysosomal damage and organelle interaction
Selected publications
1. Paddar MA , Wang F , Trosdal ES, Hendrix E , He Y , Salemi M, Mudd M, Jia J, Duque TLA , Javed R, Phinney B, Deretic V. Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function. eLife. 2024
2. Lee CS, Shang R, Wang F, Khayambashi P, Wang H, Araujo G, Puri K, Vlodavsky I, Hussein B, Rodrigues B. Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction. Diabetes. 2024 Aug 1;73(8):1300-1316.
3. Wang F, Trosdal ES, Paddar MA, Duque TLA, Allers L, Mudd M, Akepati PR, Javed R, Jia J, Salemi M, Phinney B, Deretic V. The role of ATG5 beyond Atg8ylation and autophagy. Autophagy. 2024 Feb;20(2):448-450.
4. Jia J, Wang F, Bhujabal Z, Peters R, Mudd M, Duque T, Allers L, Javed R, Salemi M, Behrends C, Phinney B, Johansen T, Deretic V. Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage. Autophagy. 2023 Jun;19(6):1893-1895.
5. Wang F, Peters R, Jia J, Mudd M, Salemi M, Allers L, Javed R, Duque TLA, Paddar MA, Trosdal ES, Phinney B, Deretic V. ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion. Developmental Cell. 2023 May 22;58(10):866-884.e8.
6. Deretic V, Wang F. Autophagy is part of the answer to tuberculosis. Nature Microbiology. 2023 May;8(5):762-763.
7. Jia J, Wang F, Bhujabal Z, Peters R, Mudd M, Duque T, Allers L, Javed R, Salemi M, Behrends C, Phinney B, Johansen T, Deretic V. Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage. The Journal of Cell Biology. 2022 Nov 7;221(11).
8. Wang F, Pulinilkunnil T, Flibotte S, Nislow C, Vlodavsky I, Hussein B, Rodrigues B. Heparanase protects the heart against chemical or ischemia/reperfusion injury. Journal of Molecular and Cellular Cardiology. 2019 Jun; 131:29-40.
9. Wang F, Jia J, Rodrigues B. Autophagy, metabolic disease, and pathogenesis of heart dysfunction. Canadian Journal of Cardiology. 2017 Jul;33(7):850-859.
10. Zhang D, Wang F, Lal N, Chiu AP, Wan A, Jia J, Bierende D, Flibotte S, Sinha S, Asadi A, Hu X, Taghizadeh F, Pulinilkunnil T, Nislow C, Vlodavsky I, Johnson JD, Kieffer TJ, Hussein B, Rodrigues B. Heparanase overexpression induces glucagon resistance and protects animals from chemically induced diabetes. Diabetes. 2017 Jan;66(1):45-57.
11. Wang F, Jia J, Lal N, Zhang D, Chiu AP, Wan A, Vlodavsky I, Hussein B, Rodrigues B. High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature. Cardiovascular Research. 2016 Dec;112(3):656-668.
